CHRNA7
MOLECULAR TARGETcholinergic receptor nicotinic alpha 7 subunit
CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CHRNA7
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Nicotine Nicotine is highly toxic alkaloid. It is | 4.38 | 79 |
| 2 | mg624 | 2.20 | 8 |
| 3 | Lobeline | 1.95 | 6 |
| 4 | Mecamylamine | 1.39 | 3 |
| 5 | Tilorone | 1.39 | 3 |
| 6 | Dimethylphenylpiperazinium Iodide | 1.10 | 2 |
| 7 | Anabasine | 0.69 | 1 |
| 8 | Arecoline | 0.69 | 1 |
| 9 | Choline | 0.69 | 1 |
| 10 | Kynurenic Acid | 0.69 | 1 |
About CHRNA7 as a Drug Target
CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented CHRNA7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CHRNA7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.