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Arecoline

An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.

299+ PubMed studies analyzed · 6 RCTs · Evidence Score: 39.4

Research Domains

Arecoline has been studied across 25 research domains including 🔬 Oncology, 🔬 Inflammation, 🫁 Liver & Detox, 🧘 Stress & Anxiety, 🔥 Metabolic. The primary research focus is 🔬 Oncology with 22% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Arecoline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Mecamylamine
11 shared targets
Lobeline
11 shared targets
Dimethylphenylpiperazinium
11 shared targets
Nicotine
12 shared targets
Muscarine
9 shared targets
acetylcholine
7 shared targets
Scopolamine
7 shared targets
Hyoscyamine
8 shared targets
Pilocarpine
7 shared targets
N-Methylscopolamine
6 shared targets
Loading evidence profile...

This evidence profile for Arecoline is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.