BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Lobeline

An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.

300+ PubMed studies analyzed · 3 RCTs · Evidence Score: 41.8

Research Domains

Lobeline has been studied across 18 research domains including 🌤️ Mood & Depression, 🧠 Focus & Attention, 🫁 Respiratory, ❤️ Cardiovascular, 🧘 Stress & Anxiety. The primary research focus is 🌤️ Mood & Depression with 17% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Lobeline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Mecamylamine
12 shared targets
Dimethylphenylpiperazinium
11 shared targets
Arecoline
11 shared targets
Nicotine
12 shared targets
Ibogaine
6 shared targets
Dihydro-beta-Erythroidine
4 shared targets
mg624
10 shared targets
Anabasine
3 shared targets
desnitroimidacloprid
2 shared targets
Ondansetron
7 shared targets
Loading evidence profile...

This evidence profile for Lobeline is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.