An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
Lobeline has been studied across 18 research domains including 🌤️ Mood & Depression, 🧠 Focus & Attention, 🫁 Respiratory, ❤️ Cardiovascular, 🧘 Stress & Anxiety. The primary research focus is 🌤️ Mood & Depression with 17% of studies addressing this area.
The following compounds share molecular targets with Lobeline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Lobeline is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.