CLK1
MOLECULAR TARGETCDC like kinase 1
CLK1 (CDC like kinase 1) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CLK1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 2.48 | 11 |
| 2 | Quercetin | 1.10 | 2 |
| 3 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 4 | chrysin | 0.69 | 1 |
| 5 | egcg | 0.69 | 1 |
| 6 | fisetin | 0.69 | 1 |
| 7 | Genistein | 0.69 | 1 |
| 8 | Kaempferols | 0.69 | 1 |
| 9 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 10 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 11 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 0.69 | 1 |
| 12 | hydroxyfasudil [Supplementary Concept] | 0.69 | 1 |
| 13 | pictilisib | 0.69 | 1 |
| 14 | Sorafenib | 0.69 | 1 |
| 15 | sp600125 | 0.69 | 1 |
About CLK1 as a Drug Target
CLK1 (CDC like kinase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented CLK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CLK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.