What compounds target CP3A4?

BiohacksAI has identified 27 compounds that interact with CP3A4 (Cytochrome P450 3A4). Top compounds include: bdb chembl4748750, bdb n 7 3r 5r 7r adamantan 1 ylmethoxy 6 cyclopropyl 1 2 4 triazolo 4 3 a pyridin 3 , bdb n 7 adamantan 1 ylmethoxy 6 ethyl 1 2 4 triazolo 4 3 a pyridin 3 yl cyclopropane, bdb chembl4096341, bdb chembl4746745. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CP3A4 (Cytochrome P450 3A4)?

CP3A4 is Cytochrome P450 3A4. It is a molecular target for 27 compounds documented in PubMed bioassay data.

CP3A4

MOLECULAR TARGET

Cytochrome P450 3A4

27 compounds

CP3A4 (Cytochrome P450 3A4) is targeted by 27 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CP3A4

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb chembl4748750	0.69	1
2	bdb n 7 3r 5r 7r adamantan 1 ylmethoxy 6 cyclopropyl 1 2 4 triazolo 4 3 a pyridin 3	0.69	1
3	bdb n 7 adamantan 1 ylmethoxy 6 ethyl 1 2 4 triazolo 4 3 a pyridin 3 yl cyclopropane	0.69	1
4	bdb chembl4096341	0.69	1
5	bdb chembl4746745	0.69	1
6	bdb chembl4747534	0.69	1
7	bdb chembl4779054	0.69	1
8	bdb chembl4788862	0.69	1
9	bdb chembl3609819	0.69	1
10	bdb 1r 5s 7 4 3 2 chloro 3 6 difluoro phenoxy propyl phenyl 3 9 diaza bicyclo 3 3 1	0.69	1
11	bdb r 3 6 trifluoromethyl pyridin 2 ylamino pyrrolidine 1 carboxylic acid 5 carbamoy	0.69	1
12	bdb r 3 3 trifluoromethyl pyridin 2 ylamino pyrrolidine 1 carboxylic acid 5 carbamoy	0.69	1
13	bdb r 3 5 trifluoromethyl pyridin 2 ylamino pyrrolidine 1 carboxylic acid 5 carbamoy	0.69	1
14	bdb s 3 3 trifluoromethyl pyridin 2 ylamino pyrrolidine 1 carboxylic acid 5 carbamoy	0.69	1
15	bdb 1 7 aza bicyclo 2 2 1 hept 7 yl 2 2 3 5 dimethyl phenyl 3 s 2 2 isoquinolin 5 yl	0.69	1
16	bdb 1r 5r 3 4 3 2 chloro 3 6 difluorophenoxy propyl phenyl n cyclopropyl n 2 3 dichl	0.69	1
17	bdb 3 6 4 1r 4s 5 oxa 2 aza bicyclo 2 2 1 heptan 2 yl piperidin 1 yl 4 methyl 1h ben	0.69	1
18	bdb 6 aza pat chembl2334756	0.69	1
19	bdb chembl2158890	0.69	1
20	bdb chembl2334758	0.69	1
21	bdb chembl2334759	0.69	1
22	bdb chembl2334763	0.69	1
23	bdb chembl2334764	0.69	1
24	bdb chembl3422102	0.69	1
25	bdb chembl3582240	0.69	1
26	bdb chembl4061129	0.69	1
27	bdb oz 209 dispiro adamantane 2 2 1 3 5 trioxolane 4 1 cyclohexane 4 ylmethanamine c	0.69	1

About CP3A4 as a Drug Target

CP3A4 (Cytochrome P450 3A4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 27 compounds with documented CP3A4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CP3A4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.