GABRA2
MOLECULAR TARGETgamma-aminobutyric acid type A receptor subunit alpha2
GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2) is targeted by 13 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GABRA2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | gamma-Aminobutyric Acid | 3.43 | 30 |
| 2 | Pregnanolone | 2.20 | 8 |
| 3 | Bicuculline | 1.39 | 3 |
| 4 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.10 | 2 |
| 5 | chrysin | 1.10 | 2 |
| 6 | Androsterone | 1.10 | 2 |
| 7 | Etomidate Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or | 1.10 | 2 |
| 8 | Ciprofloxacin | 0.69 | 1 |
| 9 | Eszopiclone | 0.69 | 1 |
| 10 | Etiocholanolone | 0.69 | 1 |
| 11 | Ondansetron | 0.69 | 1 |
| 12 | Picrotoxin | 0.69 | 1 |
| 13 | Triiodothyronine | 0.69 | 1 |
About GABRA2 as a Drug Target
GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 13 compounds with documented GABRA2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GABRA2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.