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Pregnanolone

A pregnane found in the urine of PREGNANT PEOPLE and sows. It has anesthetic, hypnotic, and sedative properties.

298+ PubMed studies analyzed · 10 RCTs · Evidence Score: 42.7

Research Domains

Pregnanolone has been studied across 21 research domains including 🧘 Stress & Anxiety, 🧬 Hormones, 😴 Sleep, 🌤️ Mood & Depression, 🧠 Learning. The primary research focus is 🧘 Stress & Anxiety with 47% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Pregnanolone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Bicuculline
17 shared targets
Etomidate
16 shared targets
Ciprofloxacin
15 shared targets
Etiocholanolone
16 shared targets
Androsterone
18 shared targets
Picrotoxin
15 shared targets
gamma-Aminobutyric
17 shared targets
Ondansetron
16 shared targets
Triiodothyronine
18 shared targets
flumazenil
6 shared targets
Loading evidence profile...

This evidence profile for Pregnanolone is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.