GPX1
MOLECULAR TARGETglutathione peroxidase 1
GPX1 (glutathione peroxidase 1) is targeted by 23 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GPX1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | amlexanox | 1.10 | 2 |
| 2 | DEAD-box RNA Helicases | 0.69 | 1 |
| 3 | Thioctic Acid | 0.69 | 1 |
| 4 | vinpocetine | 0.69 | 1 |
| 5 | cefatrizine | 0.69 | 1 |
| 6 | Cefazolin | 0.69 | 1 |
| 7 | Cefdinir | 0.69 | 1 |
| 8 | Cefixime | 0.69 | 1 |
| 9 | Cefmenoxime | 0.69 | 1 |
| 10 | Cefotetan | 0.69 | 1 |
| 11 | Cefoxitin | 0.69 | 1 |
| 12 | Cefpodoxime | 0.69 | 1 |
| 13 | Cefprozil | 0.69 | 1 |
| 14 | ceftazidime | 0.69 | 1 |
| 15 | Ceftibuten | 0.69 | 1 |
| 16 | Cephaloglycin | 0.69 | 1 |
| 17 | Dipyrone | 0.69 | 1 |
| 18 | Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium. | 0.69 | 1 |
| 19 | Doxazosin | 0.69 | 1 |
| 20 | Irinotecan | 0.69 | 1 |
| 21 | silver sulfadiazine | 0.69 | 1 |
| 22 | stx64 | 0.69 | 1 |
| 23 | Thioctic Acid | 0.69 | 1 |
About GPX1 as a Drug Target
GPX1 (glutathione peroxidase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 23 compounds with documented GPX1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GPX1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.