A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
Irinotecan has been studied across 14 research domains including 🔬 Oncology, 🦠 Gut & Microbiome, 🫁 Liver & Detox, ⚡ Energy & Fatigue, ⏳ Longevity & Aging. The primary research focus is 🔬 Oncology with 67% of studies addressing this area.
The following compounds share molecular targets with Irinotecan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Irinotecan is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.