HEAT
MOLECULAR TARGETheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (human)
HEAT (heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (human)) is targeted by 8 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting HEAT
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | triolimus [Supplementary Concept] | 2.64 | 13 |
| 2 | cannabidiol | 1.10 | 2 |
| 3 | Hexachlorophene | 1.10 | 2 |
| 4 | Thapsigargin | 1.10 | 2 |
| 5 | Mianserin | 0.69 | 1 |
| 6 | ag490 | 0.69 | 1 |
| 7 | Levonorgestrel | 0.69 | 1 |
| 8 | Norgestrel | 0.69 | 1 |
About HEAT as a Drug Target
HEAT (heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 8 compounds with documented HEAT interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
HEAT inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.