BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Mianserin

A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.

299+ PubMed studies analyzed · 45 RCTs · Evidence Score: 48.4

Research Domains

Mianserin has been studied across 14 research domains including 🌤️ Mood & Depression, 🧠 Focus & Attention, 😴 Sleep, ❤️ Cardiovascular, 💊 Pain. The primary research focus is 🌤️ Mood & Depression with 41% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Mianserin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Cyproheptadine
46 shared targets
Quetiapine
37 shared targets
Amitriptyline
46 shared targets
Nortriptyline
43 shared targets
Promethazine
39 shared targets
Pergolide
31 shared targets
Amoxapine
40 shared targets
Yohimbine
28 shared targets
Dihydroergotamine
29 shared targets
Cinnarizine
28 shared targets
Loading evidence profile...

This evidence profile for Mianserin is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.