KCNQ1
MOLECULAR TARGETpotassium voltage-gated channel subfamily Q member 1
KCNQ1 (potassium voltage-gated channel subfamily Q member 1) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting KCNQ1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Oleic Acid | 1.39 | 3 |
| 2 | Calcimycin | 1.39 | 3 |
| 3 | Chlorhexidine | 1.39 | 3 |
| 4 | dihydrorotenone | 1.39 | 3 |
| 5 | Hexachlorophene | 1.39 | 3 |
| 6 | Nortriptyline | 1.10 | 2 |
| 7 | Sphingosine | 1.10 | 2 |
| 8 | Duloxetine Hydrochloride | 0.69 | 1 |
| 9 | vinpocetine | 0.69 | 1 |
| 10 | 17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as | 0.69 | 1 |
| 11 | Bisphenol A-Glycidyl Methacrylate | 0.69 | 1 |
| 12 | Calcitriol | 0.69 | 1 |
| 13 | Clotrimazole | 0.69 | 1 |
| 14 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 0.69 | 1 |
| 15 | Ethinyl Estradiol | 0.69 | 1 |
| 16 | Niflumic Acid | 0.69 | 1 |
| 17 | Nisoldipine | 0.69 | 1 |
| 18 | Thioridazine | 0.69 | 1 |
About KCNQ1 as a Drug Target
KCNQ1 (potassium voltage-gated channel subfamily Q member 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented KCNQ1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
KCNQ1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.