What compounds target MMP2?

BiohacksAI has identified 24 compounds that interact with MMP2 (72 kDa type IV collagenase). Top compounds include: epigalocatechin gallate, ubenimex, isoliquiritigenin, taxifolin, oxyquinoline. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is MMP2 (72 kDa type)?

MMP2 is 72 kDa type IV collagenase. It is a molecular target for 24 compounds documented in PubMed bioassay data.

MMP2

MOLECULAR TARGET

72 kDa type IV collagenase

24 compounds

MMP2 (72 kDa type IV collagenase) is targeted by 24 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting MMP2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	epigalocatechin gallate	5.40	220
2	ubenimex	4.57	96
3	isoliquiritigenin	4.50	89
4	taxifolin	4.17	64
5	oxyquinoline	3.85	46
6	amentoflavone	3.76	42
7	cgs 27023a	3.76	42
8	marimastat	3.47	31
9	ilomastat	3.40	29
10	actinonin	3.18	23
11	pyrogallol	3.14	22
12	oxyresveratrol	3.04	20
13	prinomastat	2.94	18
14	gingkolic acid	2.71	14
15	cts 1027	2.64	13
16	batimastat	2.48	11
17	robustaflavone	2.48	11
18	artepillin	2.20	8
19	tiludronic acid	2.08	7
20	3 nitrophenylaminomethylenediphosphonic acid	2.08	7
21	ro 319790	1.79	5
22	ageladine a	1.79	5
23	bdb 2 adamantyloxy 4 methoxyphenyl sulfonyl amino n hydroxyacetamide chembl227567	0.69	1
24	bdb chembl1738748	0.69	1

About MMP2 as a Drug Target

MMP2 (72 kDa type IV collagenase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 24 compounds with documented MMP2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

MMP2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.