PIK3CG
MOLECULAR TARGETphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) is targeted by 8 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIK3CG
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ly294002 | 3.30 | 26 |
| 2 | pictilisib | 3.22 | 24 |
| 3 | alpelisib | 2.30 | 9 |
| 4 | Wortmannin | 2.08 | 7 |
| 5 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 1.10 | 2 |
| 6 | torin 1 | 1.10 | 2 |
| 7 | Quercetin | 0.69 | 1 |
| 8 | Sirolimus | 0.69 | 1 |
About PIK3CG as a Drug Target
PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 8 compounds with documented PIK3CG interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIK3CG inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.