PRKAA1
MOLECULAR TARGETprotein kinase AMP-activated catalytic subunit alpha 1
PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PRKAA1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Adenosine Monophosphate Adenine nucleotide containing | 2.08 | 7 |
| 2 | Proguanil | 1.95 | 6 |
| 3 | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | 1.61 | 4 |
| 4 | Niclosamide | 1.39 | 3 |
| 5 | Ursolic Acid | 1.10 | 2 |
| 6 | Antimycin | 1.10 | 2 |
| 7 | Oleanolic Acid | 1.10 | 2 |
| 8 | Rotenone | 1.10 | 2 |
| 9 | Berberine | 0.69 | 1 |
| 10 | Metformin | 0.69 | 1 |
| 11 | Crizotinib | 0.69 | 1 |
About PRKAA1 as a Drug Target
PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented PRKAA1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PRKAA1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.