What compounds target PRKCB?

BiohacksAI has identified 26 compounds that interact with PRKCB (protein kinase C, beta). Top compounds include: doramapimod, abemaciclib, baricitinib, gf 109203, at 9283. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PRKCB (protein kinase C,)?

PRKCB is protein kinase C, beta. It is a molecular target for 26 compounds documented in PubMed bioassay data. UniProt ID: P68403. NCBI Gene ID: 25023.

PRKCB

MOLECULAR TARGET

protein kinase C, beta

UniProt: P68403 NCBI Gene: 2502326 compounds

PRKCB (protein kinase C, beta) is targeted by 26 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PRKCB

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	doramapimod	4.06	57
2	abemaciclib	3.66	38
3	baricitinib	3.56	34
4	gf 109203	3.40	29
5	at 9283	3.09	21
6	pacritinib	3.04	20
7	pf 03758309	3.00	19
8	hymenialdisine	3.00	19
9	ruboxistaurin	2.94	18
10	go 6976	2.89	17
11	ro 316233	2.83	16
12	sotrastaurin	2.77	15
13	capivasertib	2.77	15
14	gsk 690693	2.64	13
15	zotiraciclib	2.56	12
16	balanol	2.30	9
17	decernotinib	2.20	8
18	y 39983	2.20	8
19	enzastaurin	2.08	7
20	uprosertib	1.95	6
21	ucn 01	1.79	5
22	afuresertib	1.79	5
23	ly 2090314	1.79	5
24	sb 242235	1.79	5
25	myricetin-3-O-galactopyranoside [Supplementary Concept]	0.69	1
26	Sphingosine	0.69	1

About PRKCB as a Drug Target

PRKCB (protein kinase C, beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 26 compounds with documented PRKCB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PRKCB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.