What compounds target TAOK2?

BiohacksAI has identified 29 compounds that interact with TAOK2 (TAO kinase 2). Top compounds include: alvocidib, foretinib, tozasertib, ruxolitinib, palbociclib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TAOK2 (TAO kinase 2)?

TAOK2 is TAO kinase 2. It is a molecular target for 29 compounds documented in PubMed bioassay data. UniProt ID: Q9UL54. NCBI Gene ID: 9344.

TAOK2

MOLECULAR TARGET

TAO kinase 2

UniProt: Q9UL54 NCBI Gene: 934429 compounds

TAOK2 (TAO kinase 2) is targeted by 29 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TAOK2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	alvocidib	4.52	91
2	foretinib	4.34	76
3	tozasertib	4.33	75
4	ruxolitinib	4.23	68
5	palbociclib	4.22	67
6	bosutinib	4.08	58
7	dinaciclib	3.87	47
8	pazopanib	3.69	39
9	bms 387032	3.47	31
10	tae 684	3.43	30
11	fedratinib	3.40	29
12	gilteritinib	3.40	29
13	at 7519	3.33	27
14	lestaurtinib	3.04	20
15	pacritinib	3.04	20
16	ruboxistaurin	2.94	18
17	r 406	2.83	16
18	cediranib	2.83	16
19	milciclib	2.77	15
20	pha 665752	2.71	14
21	gsk 690693	2.64	13
22	ast 487	2.56	12
23	zotiraciclib	2.56	12
24	raf 265	2.48	11
25	golvatinib	2.20	8
26	rg 547	2.08	7
27	pf 03814735	1.79	5
28	Crizotinib	0.69	1
29	Sorafenib	0.69	1

About TAOK2 as a Drug Target

TAOK2 (TAO kinase 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 29 compounds with documented TAOK2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TAOK2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.