What compounds target TNK1?

BiohacksAI has identified 44 compounds that interact with TNK1 (tyrosine kinase non receptor 1). Top compounds include: erlotinib, tofacitinib, foretinib, tozasertib, ponatinib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TNK1 (tyrosine kinase non)?

TNK1 is tyrosine kinase non receptor 1. It is a molecular target for 44 compounds documented in PubMed bioassay data. UniProt ID: Q13470. NCBI Gene ID: 8711.

TNK1

MOLECULAR TARGET

tyrosine kinase non receptor 1

UniProt: Q13470 NCBI Gene: 871144 compounds

TNK1 (tyrosine kinase non receptor 1) is targeted by 44 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TNK1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	erlotinib	5.55	256
2	tofacitinib	4.65	104
3	foretinib	4.34	76
4	tozasertib	4.33	75
5	ponatinib	4.26	70
6	ceritinib	4.19	65
7	midostaurin	3.85	46
8	pazopanib	3.69	39
9	nintedanib	3.61	36
10	baricitinib	3.56	34
11	tae 684	3.43	30
12	fedratinib	3.40	29
13	gilteritinib	3.40	29
14	mln 8054	3.33	27
15	dabrafenib	3.30	26
16	alisertib	3.30	26
17	entrectinib	3.18	23
18	rociletinib	3.18	23
19	lestaurtinib	3.04	20
20	pacritinib	3.04	20
21	danusertib	2.94	18
22	r 406	2.83	16
23	k 252a	2.83	16
24	milciclib	2.77	15
25	kw 2449	2.64	13
26	ast 487	2.56	12
27	raf 265	2.48	11
28	defactinib	2.48	11
29	mk 5108	2.48	11
30	poziotinib	2.48	11
31	bms 754807	2.30	9
32	azd 1480	2.30	9
33	su 014813	2.20	8
34	rebastinib	2.20	8
35	gsk 1070916	2.20	8
36	decernotinib	2.20	8
37	enzastaurin	2.08	7
38	asp 3026	2.08	7
39	fostamatinib	2.08	7
40	glesatinib	2.08	7
41	pf 03814735	1.79	5
42	Sorafenib	1.61	4
43	Axitinib	1.10	2
44	Crizotinib	0.69	1

About TNK1 as a Drug Target

TNK1 (tyrosine kinase non receptor 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 44 compounds with documented TNK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TNK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.