TRPC6
MOLECULAR TARGETtransient receptor potential cation channel subfamily C member 6
TRPC6 (transient receptor potential cation channel subfamily C member 6) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TRPC6
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Hyoscyamine | 1.39 | 3 |
| 2 | Carvedilol | 1.39 | 3 |
| 3 | Propantheline | 1.39 | 3 |
| 4 | Methylene Blue | 1.10 | 2 |
| 5 | Hexachlorophene | 1.10 | 2 |
| 6 | Promazine | 1.10 | 2 |
| 7 | Promethazine | 1.10 | 2 |
| 8 | propionylpromazine hydrochloride | 1.10 | 2 |
| 9 | Thioridazine | 1.10 | 2 |
| 10 | triflupromazine hydrochloride | 1.10 | 2 |
| 11 | Arachidonic Acid | 0.69 | 1 |
| 12 | Duloxetine Hydrochloride | 0.69 | 1 |
| 13 | Amoxapine | 0.69 | 1 |
| 14 | Fluspirilene | 0.69 | 1 |
| 15 | Lysophosphatidylcholines Derivatives of PHOSPHATIDYLCHOLINES obtained by their partial hydrolysis which removes | 0.69 | 1 |
About TRPC6 as a Drug Target
TRPC6 (transient receptor potential cation channel subfamily C member 6) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented TRPC6 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TRPC6 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.