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Promethazine Hydrochloride

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.

121+ PubMed studies analyzed · 6 RCTs · Evidence Score: 45.3

Research Domains

Promethazine Hydrochloride has been studied across 10 research domains including 🧠 Focus & Attention, 💊 Pain, 🫁 Liver & Detox, ✨ Skin & Hair, 🔬 Inflammation. The primary research focus is 🧠 Focus & Attention with 7% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Promethazine Hydrochloride, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Thioridazine
35 shared targets
Promazine
19 shared targets
triflupromazine
25 shared targets
Nicardipine
22 shared targets
Cetylpyridinium
20 shared targets
Flutamide
22 shared targets
Budesonide
17 shared targets
Lynestrenol
18 shared targets
Acetaldehyde
15 shared targets
propionylpromazine
18 shared targets
Loading evidence profile...

This evidence profile for Promethazine Hydrochloride is generated deterministically from 121 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.