What compounds target USP1?

BiohacksAI has identified 25 compounds that interact with USP1 (ubiquitin specific peptidase 1). Top compounds include: Daunorubicin, Hexachlorophene, Idarubicin, Nitroprusside, Arachidonic Acid. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is USP1 (ubiquitin specific peptidase)?

USP1 is ubiquitin specific peptidase 1. It is a molecular target for 25 compounds documented in PubMed bioassay data. UniProt ID: AAH18745. NCBI Gene ID: 7398.

USP1

MOLECULAR TARGET

ubiquitin specific peptidase 1

UniProt: AAH18745 NCBI Gene: 739825 compounds

USP1 (ubiquitin specific peptidase 1) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting USP1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Daunorubicin	1.10	2
2	Hexachlorophene	1.10	2
3	Idarubicin	1.10	2
4	Nitroprusside	1.10	2
5	Arachidonic Acid	0.69	1
6	Dehydroepiandrosterone Sulfate	0.69	1
7	Oleic Acid	0.69	1
8	plumbagin [Supplementary Concept]	0.69	1
9	Adapalene	0.69	1
10	Aurintricarboxylic Acid	0.69	1
11	Benzethonium Bactericidal cationic quaternary ammonium surfactant used as	0.69	1
12	candesartan cilexetil [Supplementary Concept]	0.69	1
13	Cetylpyridinium Cationic bactericidal surfactant used as	0.69	1
14	Chlorhexidine	0.69	1
15	Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium.	0.69	1
16	Estramustine	0.69	1
17	Ethidium	0.69	1
18	ethopropazine hydrochloride	0.69	1
19	Histamine	0.69	1
20	juglone hydroxylase [Supplementary Concept] catalyzes	0.69	1
21	Nitrofurantoin	0.69	1
22	o-Phthalaldehyde	0.69	1
23	Sodium Dodecyl Sulfate	0.69	1
24	streptonigrin	0.69	1
25	Suramin	0.69	1

About USP1 as a Drug Target

USP1 (ubiquitin specific peptidase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented USP1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

USP1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.