VOLTAGE-GATED
MOLECULAR TARGETVoltage-gated inwardly rectifying potassium channel KCNH2 (human)
VOLTAGE-GATED (Voltage-gated inwardly rectifying potassium channel KCNH2 (human)) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting VOLTAGE-GATED
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Sertraline | 1.10 | 2 |
| 2 | Astemizole Antihistamine drug now withdrawn from | 1.10 | 2 |
| 3 | Carvedilol | 1.10 | 2 |
| 4 | dofetilide | 1.10 | 2 |
| 5 | Flunarizine Flunarizine is | 1.10 | 2 |
| 6 | Perphenazine | 1.10 | 2 |
| 7 | Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent | 0.69 | 1 |
| 8 | Cefiderocol | 0.69 | 1 |
| 9 | Celecoxib | 0.69 | 1 |
| 10 | Quinidine | 0.69 | 1 |
About VOLTAGE-GATED as a Drug Target
VOLTAGE-GATED (Voltage-gated inwardly rectifying potassium channel KCNH2 (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented VOLTAGE-GATED interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
VOLTAGE-GATED inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.