Effects of PIP2 hydrolysis
REACTOME PATHWAYThe Effects of PIP2 hydrolysis pathway (Reactome ID: R-HSA-114508) involves 2 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Effects of PIP2 hydrolysis
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hyoscyamine | — | 296 |
| 2 | Carvedilol | — | 296 |
| 3 | Propantheline | — | 73 |
| 4 | Methylene Blue | — | 200 |
| 5 | Hexachlorophene | — | 300 |
| 6 | Promazine | — | 40 |
| 7 | Promethazine | — | 121 |
| 8 | propionylpromazine hydrochloride | — | 2 |
| 9 | Thioridazine | — | 35 |
| 10 | triflupromazine hydrochloride | — | 12 |
| 11 | Arachidonic Acid | — | 245 |
| 12 | Duloxetine Hydrochloride | — | 993 |
| 13 | Amoxapine | — | 259 |
| 14 | Fluspirilene | — | 74 |
| 15 | Lysophosphatidylcholines Derivatives of PHOSPHATIDYLCHOLINES obtained by their partial hydrolysis which removes | — | 300 |
| 16 | kml29 | — | 6 |
About the Effects of PIP2 hydrolysis Pathway
The Effects of PIP2 hydrolysis pathway is catalogued in Reactome (ID: R-HSA-114508) and involves 2 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MGLL, TRPC6.