PI3K events in ERBB4 signaling
REACTOME PATHWAYThe PI3K events in ERBB4 signaling pathway (Reactome ID: R-HSA-1250342) involves 2 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting PI3K events in ERBB4 signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | pictilisib | — | 25 |
| 2 | Wortmannin | — | 300 |
| 3 | ly294002 | — | 11 |
| 4 | alpelisib | — | 227 |
| 5 | Sirolimus | — | 300 |
| 6 | torin 1 | — | 10 |
| 7 | Quercetin | — | 300 |
| 8 | Afatinib | — | 297 |
| 9 | Dasatinib | — | 299 |
| 10 | sp600125 | — | 117 |
| 11 | tyrphostin ag 1478 | — | 4 |
About the PI3K events in ERBB4 signaling Pathway
The PI3K events in ERBB4 signaling pathway is catalogued in Reactome (ID: R-HSA-1250342) and involves 2 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ERBB4, PIK3R1.