PLCG1 events in ERBB2 signaling
REACTOME PATHWAYThe PLCG1 events in ERBB2 signaling pathway (Reactome ID: R-HSA-1251932) involves 2 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting PLCG1 events in ERBB2 signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Afatinib | — | 297 |
| 3 | tyrphostin ag 1478 | — | 4 |
| 4 | ag490 | — | 14 |
| 5 | tyrphostin 1 | — | 1 |
About the PLCG1 events in ERBB2 signaling Pathway
The PLCG1 events in ERBB2 signaling pathway is catalogued in Reactome (ID: R-HSA-1251932) and involves 2 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include EGFR, ERBB2.