Vitamin C (ascorbate) metabolism
REACTOME PATHWAYThe Vitamin C (ascorbate) metabolism pathway (Reactome ID: R-HSA-196836) involves 4 genes and is affected by 21 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Vitamin C (ascorbate) metabolism
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Resveratrol | — | 298 |
| 2 | Glucose | — | 294 |
| 3 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 4 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 5 | Vitamin K 3 | — | 300 |
| 6 | Methylene Blue | — | 200 |
| 7 | Anthralin | — | 299 |
| 8 | Calcimycin | — | 216 |
| 9 | Demeclocycline | — | 5 |
| 10 | Edaravone | — | 298 |
| 11 | Catechin | — | 300 |
| 12 | Masoprocol | — | 300 |
| 13 | Oxytetracycline | — | 300 |
| 14 | Tetracycline | — | 300 |
| 15 | Genistein | — | 300 |
| 16 | Kaempferols | — | 300 |
| 17 | Anisomycin | — | 247 |
| 18 | cycloheximide | — | 300 |
| 19 | Emetine | — | 298 |
| 20 | Ascorbic Acid | — | 299 |
| 21 | Ascorbic Acid | — | 300 |
About the Vitamin C (ascorbate) metabolism Pathway
The Vitamin C (ascorbate) metabolism pathway is catalogued in Reactome (ID: R-HSA-196836) and involves 4 genes. In the BiohacksAI corpus, 21 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GSTO1, SLC23A1, SLC2A1, SLC2A3.