Ephrin signaling
REACTOME PATHWAYThe Ephrin signaling pathway (Reactome ID: R-HSA-3928664) involves 7 genes and is affected by 18 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Ephrin signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Sorafenib | — | 300 |
| 3 | Crizotinib | — | 298 |
| 4 | tyrphostin ag 1478 | — | 4 |
| 5 | Afatinib | — | 297 |
| 6 | kenpaullone | — | 8 |
| 7 | Resveratrol | — | 298 |
| 8 | Quercetin | — | 300 |
| 9 | Adenosine Monophosphate Adenine nucleotide containing | — | 300 |
| 10 | alsterpaullone | — | 12 |
| 11 | monorden | — | 8 |
| 12 | Niclosamide | — | 299 |
| 13 | Rosmarinic Acid | — | 300 |
| 14 | Genistein | — | 300 |
| 15 | egcg | — | 300 |
| 16 | Acetic Acid Product of | — | 300 |
| 17 | Axitinib | — | 298 |
| 18 | pictilisib | — | 25 |
About the Ephrin signaling Pathway
The Ephrin signaling pathway is catalogued in Reactome (ID: R-HSA-3928664) and involves 7 genes. In the BiohacksAI corpus, 18 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include EPHB1, EPHB2, EPHB3, EPHB4, EPHB6.