What compounds affect the Myogenesis pathway?

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Myogenesis pathway (Reactome ID: R-HSA-525793). These compounds target 5 genes within this pathway.

What genes are in the Myogenesis pathway?

The Myogenesis pathway involves 5 genes. Key genes include: ABL1, CDC42, MAPK11, MAPK12, MAPK14.

Myogenesis

REACTOME PATHWAY

Reactome: R-HSA-5257935 genes29 compounds

The Myogenesis pathway (Reactome ID: R-HSA-525793) involves 5 genes and is affected by 29 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

ABL1 CDC42 MAPK11 MAPK12 MAPK14

Compounds Affecting Myogenesis

#	Compound	Targets Hit	Studies
1	Sorafenib	—	300
2	Dasatinib	—	299
3	Afatinib	—	297
4	Anisomycin	—	247
5	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	—	300
6	withaferin	—	300
7	tyrphostin ag 1478	—	4
8	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
9	Quercetin	—	300
10	Axitinib	—	298
11	Crizotinib	—	298
12	Avapritinib	—	246
13	Biotin	—	297
14	19-((1'S,4'R)-4'-hydroxy-1'-methoxy-2'-oxopentyl)geldanamycin [Supplementary Concept]	—	300
15	Imatinib Mesylate	—	300
16	triolimus [Supplementary Concept]	—	33
17	Genistein	—	300
18	pterostilbene	—	299
19	Adenosine Triphosphate	—	300
20	alpelisib	—	227
21	alsterpaullone	—	12
22	kenpaullone	—	8
23	Nocodazole Nocodazole is	—	215
24	Oxytetracycline	—	300
25	egcg	—	300
26	fisetin	—	78
27	Celecoxib	—	295
28	sp600125	—	117
29	casin	—	10

About the Myogenesis Pathway

The Myogenesis pathway is catalogued in Reactome (ID: R-HSA-525793) and involves 5 genes. In the BiohacksAI corpus, 29 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ABL1, CDC42, MAPK11, MAPK12, MAPK14.