What compounds affect the Fanconi Anemia Pathway pathway?

26 compounds in the BiohacksAI corpus have documented interactions with genes in the Fanconi Anemia Pathway pathway (Reactome ID: R-HSA-6783310). These compounds target 2 genes within this pathway.

What genes are in the Fanconi Anemia Pathway pathway?

The Fanconi Anemia Pathway pathway involves 2 genes. Key genes include: MUS81, USP1.

Fanconi Anemia Pathway

REACTOME PATHWAY

Reactome: R-HSA-67833102 genes26 compounds

The Fanconi Anemia Pathway pathway (Reactome ID: R-HSA-6783310) involves 2 genes and is affected by 26 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

MUS81 USP1

Compounds Affecting Fanconi Anemia Pathway

#	Compound	Targets Hit	Studies
1	Daunorubicin	—	298
2	Hexachlorophene	—	300
3	Idarubicin	—	299
4	Nitroprusside	—	299
5	Arachidonic Acid	—	245
6	Dehydroepiandrosterone Sulfate	—	300
7	Oleic Acid	—	112
8	plumbagin [Supplementary Concept]	—	300
9	Adapalene	—	296
10	Aurintricarboxylic Acid	—	184
11	Benzethonium Bactericidal cationic quaternary ammonium surfactant used as	—	96
12	candesartan cilexetil [Supplementary Concept]	—	300
13	Cetylpyridinium Cationic bactericidal surfactant used as	—	300
14	Chlorhexidine	—	299
15	Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium.	—	135
16	Estramustine	—	300
17	Ethidium	—	300
18	ethopropazine hydrochloride	—	2
19	Histamine	—	300
20	juglone hydroxylase [Supplementary Concept] catalyzes	—	279
21	Nitrofurantoin	—	297
22	o-Phthalaldehyde	—	300
23	Sodium Dodecyl Sulfate	—	300
24	streptonigrin	—	299
25	Suramin	—	300
26	Liraglutide	—	999

About the Fanconi Anemia Pathway Pathway

The Fanconi Anemia Pathway pathway is catalogued in Reactome (ID: R-HSA-6783310) and involves 2 genes. In the BiohacksAI corpus, 26 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MUS81, USP1.