RNA polymerase II transcribes snRNA genes
REACTOME PATHWAYThe RNA polymerase II transcribes snRNA genes pathway (Reactome ID: R-HSA-6807505) involves 5 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RNA polymerase II transcribes snRNA genes
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | N-Methylscopolamine | — | 299 |
| 2 | thiamine | — | 299 |
| 3 | Famotidine | — | 296 |
| 4 | Guanfacine | — | 294 |
| 5 | Sumatriptan | — | 298 |
| 6 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 7 | pictilisib | — | 25 |
| 8 | Sorafenib | — | 300 |
| 9 | Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on | — | 299 |
| 10 | alsterpaullone | — | 12 |
| 11 | kenpaullone | — | 8 |
About the RNA polymerase II transcribes snRNA genes Pathway
The RNA polymerase II transcribes snRNA genes pathway is catalogued in Reactome (ID: R-HSA-6807505) and involves 5 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNT2, CDK7, CDK9, POU2F1, POU2F2.