Tryptophan catabolism
REACTOME PATHWAYThe Tryptophan catabolism pathway (Reactome ID: R-HSA-71240) involves 3 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Tryptophan catabolism
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Vitamin K 3 | — | 300 |
| 2 | Miconazole | — | 298 |
| 3 | Econazole | — | 299 |
| 4 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 5 | celastrol | — | 300 |
| 6 | Kynurenine | — | 300 |
| 7 | Tryptophan | — | 300 |
About the Tryptophan catabolism Pathway
The Tryptophan catabolism pathway is catalogued in Reactome (ID: R-HSA-71240) and involves 3 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include IDO1, KYAT1, KYNU.