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Tryptophan

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

512+ PubMed studies analyzed · 82 RCTs · Evidence Score: 55.6

Research Domains

Tryptophan has been studied across 22 research domains including 🌤️ Mood & Depression, 😴 Sleep, 🫁 Liver & Detox, 🧘 Stress & Anxiety, 🔬 Oncology. The primary research focus is 🌤️ Mood & Depression with 87% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Tryptophan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Isoniazid
5 shared targets
Melatonin
7 shared targets
Tyrosine
4 shared targets
tyrosol
3 shared targets
Nateglinide
4 shared targets
Hydrogen
3 shared targets
Hydrogen
3 shared targets
Sulfides
3 shared targets
Chlormethiazole
3 shared targets
resorcinol
3 shared targets
Loading evidence profile...

This evidence profile for Tryptophan is generated deterministically from 512 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.