Synthesis of PIPs in the nucleus
REACTOME PATHWAYThe Synthesis of PIPs in the nucleus pathway (Reactome ID: R-HSA-8847453) involves 1 genes and is affected by 14 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Synthesis of PIPs in the nucleus
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Kaempferols | — | 300 |
| 2 | Thyroxine | — | 994 |
| 3 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 4 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 5 | Diiodotyrosine | — | 300 |
| 6 | Disulfiram | — | 297 |
| 7 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | — | 300 |
| 8 | gamma-Linolenic Acid | — | 300 |
| 9 | Methyldopa | — | 297 |
| 10 | Masoprocol | — | 300 |
| 11 | Oxytetracycline | — | 300 |
| 12 | piceatannol | — | 300 |
| 13 | rafoxanide | — | 172 |
| 14 | Thyroxine | — | 300 |
About the Synthesis of PIPs in the nucleus Pathway
The Synthesis of PIPs in the nucleus pathway is catalogued in Reactome (ID: R-HSA-8847453) and involves 1 genes. In the BiohacksAI corpus, 14 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PIP4K2A.