ERBB2 Activates PTK6 Signaling
REACTOME PATHWAYThe ERBB2 Activates PTK6 Signaling pathway (Reactome ID: R-HSA-8847993) involves 5 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting ERBB2 Activates PTK6 Signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Afatinib | — | 297 |
| 3 | tyrphostin ag 1478 | — | 4 |
| 4 | ag490 | — | 14 |
| 5 | tyrphostin 1 | — | 1 |
| 6 | sp600125 | — | 117 |
| 7 | Vemurafenib | — | 298 |
About the ERBB2 Activates PTK6 Signaling Pathway
The ERBB2 Activates PTK6 Signaling pathway is catalogued in Reactome (ID: R-HSA-8847993) and involves 5 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include EGFR, ERBB2, ERBB3, ERBB4, PTK6.