Plasma lipoprotein clearance
REACTOME PATHWAYThe Plasma lipoprotein clearance pathway (Reactome ID: R-HSA-8964043) involves 3 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Plasma lipoprotein clearance
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Desmosterol | — | 300 |
| 2 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 3 | Niclosamide | — | 299 |
| 4 | Pueraria | — | 300 |
| 5 | Genistein | — | 300 |
| 6 | Resveratrol | — | 298 |
| 7 | amlexanox | — | 96 |
| 8 | kenpaullone | — | 8 |
| 9 | pd98059 | — | 7 |
| 10 | Riluzole | — | 298 |
| 11 | tyrphostin ag 1295 | — | 1 |
| 12 | Hesperidin | — | 300 |
| 13 | Bosentan | — | 298 |
| 14 | piericidin | — | 32 |
| 15 | Progesterone | — | 299 |
| 16 | Gemfibrozil | — | 297 |
About the Plasma lipoprotein clearance Pathway
The Plasma lipoprotein clearance pathway is catalogued in Reactome (ID: R-HSA-8964043) and involves 3 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NPC1, NR1H2, NR1H3.