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Bosentan

A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.

298+ PubMed studies analyzed · 53 RCTs · Evidence Score: 55.1

Research Domains

Bosentan has been studied across 15 research domains including ❤️ Cardiovascular, 🫁 Respiratory, 🫁 Liver & Detox, ✨ Skin & Hair, 🔬 Inflammation. The primary research focus is ❤️ Cardiovascular with 58% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Bosentan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Atrasentan
6 shared targets
Finasteride
8 shared targets
Meloxicam
7 shared targets
Itraconazole
7 shared targets
propyl
6 shared targets
Secologanin
6 shared targets
Dimethisterone
6 shared targets
Stanozolol
7 shared targets
Endothelin-2
2 shared targets
Polidocanol
7 shared targets
Loading evidence profile...

This evidence profile for Bosentan is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.