Question 1

What compounds affect the Transport to the Golgi and subsequent modification pathway?

Accepted Answer

28 compounds in the BiohacksAI corpus have documented interactions with genes in the Transport to the Golgi and subsequent modification pathway (Reactome ID: R-HSA-948021). These compounds target 23 genes within this pathway.

Question 2

What genes are in the Transport to the Golgi and subsequent modification pathway?

Accepted Answer

The Transport to the Golgi and subsequent modification pathway involves 23 genes. Key genes include: CSNK1D, F5, FOLR1, GRIA1, INS, MAN2A1, TUBA1A, TUBA1B, TUBA1C, TUBA3C.

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Nocodazole Nocodazole is	—	215
3	Vincristine	—	299
4	Noscapine	—	300
5	Podophyllotoxin	—	14
6	Demecolcine	—	246
7	Maytansine	—	300
8	vinblastine sulfate	—	81
9	Vorinostat	—	299
10	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid	—	300
11	Glutamic Acid	—	297
12	Glutamic Acid	—	300
13	Piracetam	—	300
14	aniracetam	—	110
15	Digitoxin	—	300
16	Digoxin	—	299
17	Flutamide	—	298
18	m084	—	2
19	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	—	299
20	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
21	sp600125	—	117
22	alsterpaullone	—	12
23	pictilisib	—	25
24	Pemetrexed	—	299
25	Methotrexate	—	289
26	Folic Acid	—	296
27	apixaban [Supplementary Concept]	—	997
28	Swainsonine	—	300

BiohacksAI

Transport to the Golgi and subsequent modification

Genes in this Pathway

Compounds Affecting Transport to the Golgi and subsequent modification

About the Transport to the Golgi and subsequent modification Pathway