What compounds affect the Signaling by MAPK mutants pathway?

22 compounds in the BiohacksAI corpus have documented interactions with genes in the Signaling by MAPK mutants pathway (Reactome ID: R-HSA-9652817). These compounds target 1 genes within this pathway.

What genes are in the Signaling by MAPK mutants pathway?

The Signaling by MAPK mutants pathway involves 1 genes. Key genes include: MAPK1.

Signaling by MAPK mutants

REACTOME PATHWAY

Reactome: R-HSA-96528171 genes22 compounds

The Signaling by MAPK mutants pathway (Reactome ID: R-HSA-9652817) involves 1 genes and is affected by 22 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

MAPK1

Compounds Affecting Signaling by MAPK mutants

#	Compound	Targets Hit	Studies
1	plumbagin [Supplementary Concept]	—	300
2	pd98059	—	7
3	tyrphostin ag 1478	—	4
4	alsterpaullone	—	12
5	kenpaullone	—	8
6	Clotrimazole	—	296
7	sp600125	—	117
8	fisetin	—	78
9	Progesterone	—	299
10	2-Chloroadenosine 2-Chloroadenosine.	—	300
11	Benzalkonium Compounds	—	299
12	Calcimycin	—	216
13	daph	—	2
14	Diphenhydramine	—	14
15	ha1004	—	4
16	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	—	300
17	Lithocholic Acid	—	300
18	Loratadine	—	296
19	Sorafenib	—	300
20	trametinib	—	296
21	trequinsin hydrochloride	—	1
22	withaferin	—	300

About the Signaling by MAPK mutants Pathway

The Signaling by MAPK mutants pathway is catalogued in Reactome (ID: R-HSA-9652817) and involves 1 genes. In the BiohacksAI corpus, 22 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAPK1.