Cardiogenesis
REACTOME PATHWAYThe Cardiogenesis pathway (Reactome ID: R-HSA-9733709) involves 2 genes and is affected by 21 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Cardiogenesis
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aurintricarboxylic Acid | — | 184 |
| 2 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 3 | DEAD-box RNA Helicases | — | 169 |
| 4 | Thioctic Acid | — | 298 |
| 5 | Arachidonic Acid | — | 245 |
| 6 | Oleic Acid | — | 112 |
| 7 | alpha-Linolenic Acid | — | 300 |
| 8 | candesartan cilexetil [Supplementary Concept] | — | 300 |
| 9 | Cisplatin | — | 300 |
| 10 | diallyl trisulfide | — | 246 |
| 11 | Estramustine | — | 300 |
| 12 | gamma-Linolenic Acid | — | 300 |
| 13 | Hexachlorophene | — | 300 |
| 14 | Iodoacetamide | — | 300 |
| 15 | Lithocholic Acid | — | 300 |
| 16 | Oxytetracycline | — | 300 |
| 17 | rafoxanide | — | 172 |
| 18 | Ritonavir | — | 298 |
| 19 | Thioctic Acid | — | 300 |
| 20 | Trazodone | — | 297 |
| 21 | s adenosylhomocysteine | — | 300 |
About the Cardiogenesis Pathway
The Cardiogenesis pathway is catalogued in Reactome (ID: R-HSA-9733709) and involves 2 genes. In the BiohacksAI corpus, 21 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include KAT2A, WDR5.