Early SARS-CoV-2 Infection Events
REACTOME PATHWAYThe Early SARS-CoV-2 Infection Events pathway (Reactome ID: R-HSA-9772572) involves 5 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Early SARS-CoV-2 Infection Events
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hexachlorophene | — | 300 |
| 2 | Oxytetracycline | — | 300 |
| 3 | egcg | — | 300 |
| 4 | Clotrimazole | — | 296 |
| 5 | Demeclocycline | — | 5 |
| 6 | Edaravone | — | 298 |
| 7 | torin 1 | — | 10 |
| 8 | pictilisib | — | 25 |
| 9 | Wortmannin | — | 300 |
| 10 | Diminazene | — | 300 |
| 11 | silver sulfadiazine | — | 299 |
| 12 | Novobiocin | — | 300 |
| 13 | Triamcinolone | — | 300 |
About the Early SARS-CoV-2 Infection Events Pathway
The Early SARS-CoV-2 Infection Events pathway is catalogued in Reactome (ID: R-HSA-9772572) and involves 5 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CTSL, FURIN, MAP1LC3B, PIK3C3, VCP.