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Novobiocin

An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)

300+ PubMed studies analyzed · 1 RCTs · Evidence Score: 40.6

Research Domains

Novobiocin has been studied across 13 research domains including 🔬 Oncology, ⚡ Energy & Fatigue, 🧠 Focus & Attention, 🫁 Liver & Detox, ✨ Skin & Hair. The primary research focus is 🔬 Oncology with 17% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Novobiocin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

onalespib
2 shared targets
luminespib
2 shared targets
biib021
2 shared targets
snx
2 shared targets
ganetespib
2 shared targets
pu
2 shared targets
radicicol
2 shared targets
alvespimycin
2 shared targets
Nitroprusside
2 shared targets
monorden
2 shared targets
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This evidence profile for Novobiocin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.