What compounds target ABCC2?

BiohacksAI has identified 31 compounds that interact with ABCC2 (ATP binding cassette subfamily C member 2). Top compounds include: Bosentan, Fusidic Acid, Leukotriene D4, Troglitazone, Abacavir. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ABCC2 (ATP binding cassette)?

ABCC2 is ATP binding cassette subfamily C member 2. It is a molecular target for 31 compounds documented in PubMed bioassay data. UniProt ID: Q92887. NCBI Gene ID: 1244.

ABCC2

MOLECULAR TARGET

ATP binding cassette subfamily C member 2

UniProt: Q92887 NCBI Gene: 124431 compounds

ABCC2 (ATP binding cassette subfamily C member 2) is targeted by 31 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ABCC2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Bosentan	1.10	2
2	Fusidic Acid	1.10	2
3	Leukotriene D4	1.10	2
4	Troglitazone	1.10	2
5	Abacavir	0.69	1
6	Antimycin	0.69	1
7	Bumetanide	0.69	1
8	cefaclor	0.69	1
9	cefadroxil	0.69	1
10	Cefamandole Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as	0.69	1
11	Cefmetazole	0.69	1
12	Cefoperazone Semisynthetic broad-spectrum cephalosporin with	0.69	1
13	Cefoxitin	0.69	1
14	Ceftriaxone	0.69	1
15	cefuroxime	0.69	1
16	Cephradine	0.69	1
17	Chloramphenicol	0.69	1
18	Delavirdine	0.69	1
19	Emtricitabine	0.69	1
20	Gemfibrozil	0.69	1
21	Glyburide	0.69	1
22	Irbesartan	0.69	1
23	Lamivudine	0.69	1
24	Leukotriene E4	0.69	1
25	Meloxicam	0.69	1
26	Nitrendipine	0.69	1
27	Olmesartan Medoxomil	0.69	1
28	Pioglitazone	0.69	1
29	Rimonabant	0.69	1
30	Sulindac	0.69	1
31	Trazodone	0.69	1

About ABCC2 as a Drug Target

ABCC2 (ATP binding cassette subfamily C member 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 31 compounds with documented ABCC2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ABCC2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.