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Leukotriene D4

One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)

300+ PubMed studies analyzed · 19 RCTs · Evidence Score: 45.9

Research Domains

Leukotriene D4 has been studied across 17 research domains including 🫁 Respiratory, 🔬 Inflammation, 🦴 Bone & Joint, 🔬 Oncology, 🫁 Liver & Detox. The primary research focus is 🫁 Respiratory with 25% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Leukotriene D4, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Leukotriene
3 shared targets
Leukotriene
2 shared targets
pranlukast
2 shared targets
zafirlukast
2 shared targets
bufo
3 shared targets
mylabris
3 shared targets
lycopus
3 shared targets
curculigo
3 shared targets
lithospermum
3 shared targets
anemarrhena
3 shared targets
Loading evidence profile...

This evidence profile for Leukotriene D4 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.