What compounds target ADRB2?

BiohacksAI has identified 82 compounds that interact with ADRB2 (adrenoceptor beta 2). Top compounds include: Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on, Propranolol, Levalbuterol, Levalbuterol, Alprenolol. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ADRB2 (adrenoceptor beta 2)?

ADRB2 is adrenoceptor beta 2. It is a molecular target for 82 compounds documented in PubMed bioassay data. UniProt ID: P07550. NCBI Gene ID: 154.

ADRB2

MOLECULAR TARGET

adrenoceptor beta 2

UniProt: P07550 NCBI Gene: 15482 compounds

ADRB2 (adrenoceptor beta 2) is targeted by 82 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ADRB2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on	3.97	52
2	Propranolol	3.56	34
3	Levalbuterol	3.37	28
4	Levalbuterol	3.37	28
5	Alprenolol	3.09	21
6	Epinephrine	2.83	16
7	Norepinephrine Precursor of epinephrine that is secreted by	2.83	16
8	Levalbuterol	2.64	13
9	Atenolol	2.56	12
10	Pindolol	2.56	12
11	Timolol	2.48	11
12	Reserpine	2.40	10
13	Bupranolol	2.30	9
14	Chlorhexidine	2.30	9
15	Clenbuterol	2.30	9
16	Fenoterol	2.08	7
17	Nadolol	2.08	7
18	Carvedilol	1.95	6
19	Practolol	1.95	6
20	Sotalol	1.95	6
21	Aripiprazole	1.79	5
22	Bisoprolol	1.79	5
23	Fluspirilene	1.79	5
24	Hexachlorophene	1.79	5
25	Ranolazine	1.79	5
26	Salmeterol Xinafoate	1.79	5
27	Terbutaline	1.79	5
28	Astemizole Antihistamine drug now withdrawn from	1.61	4
29	Bunolol	1.61	4
30	Cyclic AMP	1.61	4
31	Cyclic AMP	1.61	4
32	Domperidone	1.61	4
33	Doxazosin	1.61	4
34	Hydroxyzine	1.61	4
35	Loratadine	1.61	4
36	Lysergic Acid Diethylamide Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is	1.61	4
37	Nicergoline	1.61	4
38	Nisoldipine	1.61	4
39	Nylidrin	1.61	4
40	o-Phthalaldehyde	1.61	4
41	Xamoterol	1.61	4
42	Anisomycin	1.39	3
43	Carteolol	1.39	3
44	Clotrimazole	1.39	3
45	Dinitrochlorobenzene	1.39	3
46	Metaproterenol	1.39	3
47	Phenylephrine	1.39	3
48	Acebutolol	1.10	2
49	Celecoxib	1.10	2
50	Celiprolol	1.10	2

Showing top 50 of 82 compounds. Use the BiohacksAI search to explore all ADRB2 modulators.

About ADRB2 as a Drug Target

ADRB2 (adrenoceptor beta 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 82 compounds with documented ADRB2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ADRB2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.