ALOX12
MOLECULAR TARGETarachidonate 12-lipoxygenase, 12S type
ALOX12 (arachidonate 12-lipoxygenase, 12S type) is targeted by 28 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ALOX12
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Quercetin | 2.08 | 7 |
| 2 | Masoprocol | 1.95 | 6 |
| 3 | fisetin | 1.10 | 2 |
| 4 | Tyrosine | 1.10 | 2 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.10 | 2 |
| 6 | Tyrosine | 1.10 | 2 |
| 7 | butein | 1.10 | 2 |
| 8 | celastrol | 1.10 | 2 |
| 9 | Chlorhexidine | 1.10 | 2 |
| 10 | Ciclopirox | 1.10 | 2 |
| 11 | Diiodotyrosine | 1.10 | 2 |
| 12 | Disulfiram | 1.10 | 2 |
| 13 | Epinephrine | 1.10 | 2 |
| 14 | Flecainide | 1.10 | 2 |
| 15 | Fomepizole | 1.10 | 2 |
| 16 | Gliclazide | 1.10 | 2 |
| 17 | Hexachlorophene | 1.10 | 2 |
| 18 | isoetharine | 1.10 | 2 |
| 19 | Kynurenic Acid | 1.10 | 2 |
| 20 | mg624 | 1.10 | 2 |
| 21 | Phenelzine | 1.10 | 2 |
| 22 | piceatannol | 1.10 | 2 |
| 23 | Piribedil | 1.10 | 2 |
| 24 | Procarbazine | 1.10 | 2 |
| 25 | Rimonabant | 1.10 | 2 |
| 26 | scriptaid | 1.10 | 2 |
| 27 | Dipyrone | 0.69 | 1 |
| 28 | ethopropazine hydrochloride | 0.69 | 1 |
About ALOX12 as a Drug Target
ALOX12 (arachidonate 12-lipoxygenase, 12S type) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 28 compounds with documented ALOX12 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ALOX12 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.