BCHE
MOLECULAR TARGETbutyrylcholinesterase
BCHE (butyrylcholinesterase) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting BCHE
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Physostigmine | 3.71 | 40 |
| 2 | Physostigmine | 3.71 | 40 |
| 3 | ethopropazine | 1.61 | 4 |
| 4 | ethopropazine hydrochloride | 1.39 | 3 |
| 5 | Berberine | 0.69 | 1 |
| 6 | (N-methyl-C-11)-2-(4-methylamino-phenyl)-6-hydroxybenzothiazole [Supplementary Concept] neutral analog of amyloid-binding thioflavin-T (BTA) that crosses | 0.69 | 1 |
| 7 | Androstenedione | 0.69 | 1 |
| 8 | Quinidine | 0.69 | 1 |
| 9 | Reserpine | 0.69 | 1 |
About BCHE as a Drug Target
BCHE (butyrylcholinesterase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented BCHE interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
BCHE inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.