A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Physostigmine has been studied across 15 research domains including ❤️ Cardiovascular, 🧠 Focus & Attention, 🫘 Kidney, 👁️ Vision & Eye, 🧠 Memory. The primary research focus is ❤️ Cardiovascular with 8% of studies addressing this area.
The following compounds share molecular targets with Physostigmine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Physostigmine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.