EDNRA
MOLECULAR TARGETendothelin receptor type A
EDNRA (endothelin receptor type A) is targeted by 16 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting EDNRA
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | amiodarone | 4.51 | 90 |
| 2 | Bosentan | 3.09 | 21 |
| 3 | Atrasentan | 2.83 | 16 |
| 4 | sitaxentan | 2.48 | 11 |
| 5 | ambrisentan | 2.48 | 11 |
| 6 | bms 182874 | 2.40 | 10 |
| 7 | endothelin | 2.40 | 10 |
| 8 | exisulind | 2.30 | 9 |
| 9 | pd 156707 | 2.08 | 7 |
| 10 | Sulfisoxazole | 1.95 | 6 |
| 11 | sb 209670 | 1.95 | 6 |
| 12 | pd 156707 sodium | 1.95 | 6 |
| 13 | bms 248360 | 1.79 | 5 |
| 14 | Sulfamethoxazole | 1.10 | 2 |
| 15 | Fluoxetine | 0.69 | 1 |
| 16 | Irbesartan | 0.69 | 1 |
About EDNRA as a Drug Target
EDNRA (endothelin receptor type A) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 16 compounds with documented EDNRA interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
EDNRA inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.