BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Atrasentan

A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.

298+ PubMed studies analyzed · 37 RCTs · Evidence Score: 51.8

Research Domains

Atrasentan has been studied across 19 research domains including 🫘 Kidney, 🔬 Oncology, 🔥 Metabolic, ❤️ Cardiovascular, 🔬 Inflammation. The primary research focus is 🫘 Kidney with 33% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Atrasentan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Bosentan
6 shared targets
Leuprolide
5 shared targets
Endothelin-2
2 shared targets
Minocycline
6 shared targets
Nateglinide
4 shared targets
Dapsone
4 shared targets
Dexamethasone
4 shared targets
Torsemide
4 shared targets
Sulfaphenazole
4 shared targets
Iproniazid
4 shared targets
Loading evidence profile...

This evidence profile for Atrasentan is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.