HSD17B1
MOLECULAR TARGEThydroxysteroid 17-beta dehydrogenase 1
HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting HSD17B1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | isoliquiritigenin | 4.50 | 89 |
| 2 | 7 hydroxyflavone | 4.01 | 54 |
| 3 | dihydroguaiareticacid | 2.40 | 10 |
| 4 | Estrone | 2.20 | 8 |
| 5 | acetoxolone | 2.20 | 8 |
| 6 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 7 | Genistein | 0.69 | 1 |
| 8 | Kaempferols | 0.69 | 1 |
| 9 | Kaempferols | 0.69 | 1 |
| 10 | Masoprocol | 0.69 | 1 |
About HSD17B1 as a Drug Target
HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented HSD17B1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
HSD17B1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.